System modelling to Accelerate Pharmaceutical Development

The Pharma industry has undergone significant changes in recent years with many companies pursuing the development of lower risk / smaller volume products while progressing a much larger R&D pipeline. The success of this strategy is dependent on the ability to rapidly accelerate development through game changing technologies such as system modelling. This presentation will illustrate examples where the GSK simulations platform has been used to efficiently deploy system models for drug substance and drug product to support process design, control definition and verification. Other examples will illustrate the concept of a web application to facilitate the take up of modelling by not experts to assess process optimisation in a manufacturing environment, and the interplay of system modelling with machine learning and automation.


SIMEONE ZOMER | Scientific Director – Process Analytics | GSK