Charlotte Lee-Sinclair

Principal consultant and founder, Third Culture Ventures

Charlotte is the principal consultant and founder of Third Culture Ventures, a consulting firm specialising in digital therapeutics go-to-market strategies.

She’s the former Chief of Staff and UK Director of Big Health, a market leading mental health digital therapeutics company. Under her helm the UK business grew from a two person £1M Innovate UK grant-funded project to a business after three years.

Notable achievements include:

  • Securing national reimbursement with the Scottish Government covering 5.5 million lives,
  • Securing national reimbursement during Covid with NHS England for all 1.3 million NHS staff,
  • Getting the first ever NICE recommendation for pure software as a treatment. Sleepio was recommended by NICE as a treatment for insomnia and insomnia symptoms – marking a paradigm shift in clinical medicine and paving the way for greater acceptance of digital therapeutics

She’s an NHS trained doctor, Big 4 consultant and digital health expert. She has deep networks in the UK digital health ecosystem after leading four digital health accelerators with DigitalHealth.London accelerator and has supported around 100 small to medium sized businesses to access the NHS.

For more information on her work, go to: