Professor of Paediatric Renal Medicine, University of Bristol
I trained as an undergraduate at University College, London. I am a Fellow of the Royal College of Physicians. My PhD was in transplantation immunology at Institute of Child Health, London. Paediatric nephrology training at Great Ormond Street Hospital, London. I set up my independent laboratory programme in glomerular cell biology in Bristol, as well as holding a post as a consultant paediatric nephrologist since 1999, with an international reputation in management of nephrotic syndromes, and a pioneer of the field of podocyte biology.
I now head Bristol Renal, a glomerular research group of approximately 45 researchers, covering all areas from cell biology, transgenic models and population cohorts and genetics (H index 79).
I was the originator of the UK Renal Rare Disease Registry (RaDaR), and am currently leading the UK nephrotic syndrome study (NephroS), as well as a major industry-academic collaboration termed NURTuRE (National Unified Renal Translational Research Enterprise). I am PI on several MRC projects, including Precision Medicine, laboratory project grants and a Global Challenges program to establish international NS cohorts.
My gene therapy program commenced in 2014, and is focused on targeting the podocyte in order to radically change the treatment of kidney diseases. I am now co-Founder and Chief Scientific Officer of Purespring Therapeutics